Mohney, L.L., Williams, R.R., Bell, T.A., Lightner, D.V.-1997
Aquaculture, 149 (3-4) : 193-202
Abstract:
Juvenile shrimp fed for 14 days on oxytetracycline (OTC) medicated feed with a potency of 1500 mg OTC/kg of feed reached a level of 3.3 microgram OTC/g of shrimp tail muscle within 4 days, as measured by the microbial agar plate diffusion assay method for oxytetracycline in tissues, approved by the Association of Official Analytical Chemists. The concentration of OTC remained between 3.3-5.2 microgram OTC/g of shrimp tail muscle from Day 4 through Day 14 of the feeding period. These concentrations were greater than the Minimum Inhibitory Concentration for sensitive organisms. By the fifth day following cessation of feeding medicated feed the drug content in shrimp tail muscle was less than the detectable limit for the method, or 0.4 microgram of OTC/g shrimp tissue.
(Univ Arizona, Dept Vet Sci, Tucson, AZ 85721, USA)
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