METHOD FOR THE PRODUCTION OF GENETICALLY MODIFIED BIVALVE TROCHOPHORE LARVAE AS A FIRST-FEED FOR FISH LARVAE

Scarpa, J.

Abstract:

Many species of marine fish larvae initially subsist on endogenous

food (i.e., yolk), but soon need live food to continue development.

This first-feeding stage is where fish culturists have often failed due

to the lack of an acceptable or correctly sized live or artificial feed.

Bivalve trochophore larvae, particularly oyster trochophores, are of

an appropriate size (40-60/ m) and nutritional quality for first-feeding

marine fish larvae. However, this swimming unshelled stage is

short-lived developing into the prodissoconch I stage at which time

the shell starts to form. The short time period for the trochophore

stage also means that a daily supply must be produced or stored.

Cryopreserved oyster trochophores are already available on a

commercial basis (trademark Trochofeed). However, storage of the

trochophores requires a source of liquid nitrogen that may not be

available to culturists. Therefore, the development of a simple and

inexpensive method for producing developmentally arrested bivalve

trochophores would be useful for many culturists.

A general method for arresting development of bivalves at or prior to

the trochophore stage is by altering the sperm DNA with ultraviolet

irradiation (UV, 254 nm). A sperm suspension from a bivalve is

obtained and placed in an open container with low sides, such as a

petri dish, so that the suspension thickness is </= 1 mm thick. The

suspension is then exposed to UV (e.g., from a germicidal bulb in a

hood) for a brief time period (15-180s) depending on sperm density

and UV power. A visual examination is made with the aid of a

microscope to determine the approximate proportion of sperm

moving. Sperm movement is used as an indicator of sperm viability

and fertilization capacity. The irradiated sperm suspension is then

used to inseminate the bivalve eggs. After the eggs have undergone

two cell divisions the egg suspension may be placed in a temperature

controlled unit set at a lower temperature to delay development or

placed at an elevated temperature to hasten development.

Ultraviolet irradiation of bivalve sperm used for insemination results

in developmental arrest of the embryo at or prior to the trochophore

stage. This has been found for a number of different bivalve species

in research on producing gynogenetic haploid offspring. Only when

irradiation exposure has been for too short a time period or with too

low an output has normal development ensued in a portion of the

larval population. Fertilization is proportional to the number of

mobile sperm and yield is proportional to the number of eggs

obtained and fertilized. At HBOI, oyster (C. virginica) and clam (M.

mercenaria) trochophore larvae have been produced consistently for

use in fish culture. The general utility of the method presented is that

it is easy and inexpensive, it can be used on any bivalve species in

which sperm and eggs are retrievable and can be kept viable in vitro,

and it virtually eliminates any chance of introducing a non-native

species into a new habitat.

(Harbor Branch Oceanographic Institution, Inc., Aquaculture Division

5600 U.S. I North, Ft. Pierce, FL 34946, USA)

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