Possibilities of androgenesis in sturgeons: sterlet as a model animal


Aquaflow Technical Leaflet 2001-29

European Network for the Dissemination of Aquaculture RTD Information (Q5CA-2000-30105) and previously FAIR-3837, URL: http://www.aquaflow.org/

Many species of the sturgeon family (Acipenseridae) are cultured throughout the world. The main interest in farming is caviar production, while in Europe, sturgeons, including the sterlet (Acipenser ruthenus) are valuable export products. As a consequence of the changes on the territory of the former Soviet Union, the reduction of spawning grounds in the wild and the dramatic decline in fisheries catches, some species, such as the Atlantic sturgeon (Acipenser sturio) are only found in increasingly small numbers.

One of the possibilities to preserve valuable genetic resources is the application of modern genetic-biotechnological methods. Among these, androgenesis – the development of an embryo containing only paternal chromosomes due to failure of the egg to participate in fertilization - is one of the possible methods and the focus of this research.

Sterlet (Acipenser ruthenus) was used as the experimental model. Albinism in males was used as a phenotypic marker. Naturally-coloured sterlet females fished from the Danube were also used. Gamma irradiation at 30 kR was used for the inactivation of the female genome. A heat shock was applied in order to restore the diploid status of eggs 85 minutes post fertilisation in a 38°C water bath for a period of 150 seconds. The subsequent fertilisation and hatching results were registered - 11.2 % fertilisation and 5.1 % hatching were achieved with successful androgenesis. Following optimisation of experimental parameters, entirely albino sterlet progeny was obtained.

These results confirm the suitability of the methodology for the preservation of genetic information in diminishing populations. When used in combination with sperm cryopreservation techniques, the given species could potentially be restored decades after the collection of milt.

For more information:

Dr. Miklós Bercsényi
Veszprém University
Deak Ferenc street 16.
8361 Keszthely, Hungary
Tel:: +36 20 971 16 055

E-mail:
bm@georgikon.hu


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