Functional role of micro-organisms in larviculture: Artemia as test organism


Aquaflow Technical Leaflet 2002-98

European Network for the Dissemination of Aquaculture RTD Information (Q5CA-2000-30105) and previously FAIR-3837, URL: http://www.aquaflow.org/

Despite the growth of the aquaculture industry over the last decades, high mortalities in the larviculture phase still remain. Until recently, antibiotics were a temporary solution, but at present there is a general trend towards a more natural suppression of opportunistic and obligate pathogens.  In recent years, several research groups have proved that new zootechnical approaches, primarily the use of selected microbiota (e.g. “mature water”, “green water”, specific micro-algae, probiotic yeasts and bacteria), result in better/more reproducible data. Now there is a consensus about the critical role of microbial interactions in the larviculture of aquatic organisms.  However, studies have failed to provide answers to the numerous hypotheses about the actual biological processes involved in these microbial interventions, mainly due to the fact that the test organisms are not cultured axenically, which results inevitably in interactions with the already present micro-organisms. Consequently, the causal effect cannot be determined unequivocally.

The purpose of this recently started project, financed by FWO-Vlaanderen (Fund for Scientific Research of the Flemish Community, 2002-2005) is therefore to study the mode of action of a limited number of microbial organisms and to verify existing hypotheses by the use of a well-known organism that can be cultured axenically.  The feedback of this functional knowledge will enable the targeted selection of micro-organisms or the optimisation of their mode of action and a better planning and understanding of experiments with other organisms, crustaceans and fish. The brine shrimp Artemia is preferred as test organism for the following reasons: 1) its nutritional requirements and culture conditions are well known and can easily be standardised; 2) an axenic culture test was recently designed and successfully applied for the selection of probiotic and pathogenic bacteria; 3) the histology of its digestive tract is relatively simple; 4) a large range of micro-organisms (bacteria, yeasts, micro-algae) is ingested by Artemia; 5) with an annual consumption of more than 1500 tons of cysts Artemia is the most important food resource in larval aquaculture.

The experimental work will focus on four hypotheses with Artemia as test organism: 1) certain micro-organisms find suitable adhesion sites in the digestive tract, where they can proliferate and are able to maintain themselves there; 2) some micro-organisms are able to inhibit pathogenic bacteria; 3) micro-organisms or components of their cells are able to induce a faster maturation of the wall of the digestive tract; 4) certain micro-organisms have a positive influence on the water quality.

The research programme will cover the following steps:

Demonstration of colonisation of the intestine by selected micro-organisms by application and/or adaptation of several methods (FISH, GFP, DFA)

Screening of micro-organisms (bacteria and algae) with an inhibiting effect on pathogens

Demonstration of the effect of selected micro-organisms on the growth of cultured aquatic organisms by the enhanced maturation of the intestine

Demonstration of the effect of microbiota on the water quality.

This project is a collaboration between the Laboratory of Aquaculture & Artemia Reference Center (Ghent University, Belgium), the Laboratory for Microbial Ecology and Technology (idem), and the Laboratory for Aquatic Ecology (Catholic University of Leuven, Belgium).

For more information:

SORGELOOS Patrick (patrick.sorgeloos@rug.ac.be)
Laboratory of Aquaculture & Artemia Reference Center - Ghent University
Rozier 44
B9000 Gent
Belgium
Phone : +32-9-264 37 54
Fax : +32-9-264 41 93

E-mail: Patrick.sorgeloos@rug.ac.be


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