Therapeutic effects of
enrofloxacin in an experimental infection with a luminescent Vibrio
harveyi in Artemia franciscana Kellog 1906
A.
Roque, B. Gomez-Gil-2003
Aquaculture,
220(1-4) : 37-42
Abstract:
Although a wide range and number of
chemotherapeutants have been developed and applied in aquaculture, there
have been no studies on the absorption of antibiotics by crustacean larvae
and, consequently, none has been reported to treat an established infection.
The aim of this study was to evaluate the therapeutic
effects of enrofloxacin during an experimental infection with the strain
PN9801 identified as Vibrio harveyi in Artemia franciscana.
Four treatments were used: (1) Nauplii experimentally
infected with V. harveyi; (2) Nauplii enriched with enrofloxacin; (3)
Nauplii enriched with enrofloxacin and, 4 h later, experimentally infected
with V. harveyi; and (4) Nauplii experimentally infected with V.
harveyi and 24 h later enriched with enrofloxacin. Survival rates were
estimated after 48 h and they were as it follows: 29%, 99%, 88% and 85% for
treatments 1, 2, 3 and 4, respectively.
This study is the first one to show some evidence
that antibiotics can, in fact, withhold the course of a bacterial infection
already established in Artemia and possibly in crustaceans.