ontogeny of gut function in marine fish larvae


I. Rřnnestad

Abstract:

Our current research focuses on ontogeny of digestive function in marine fish larvae. Particularly, the intestinal digestion and assimilation processes of dietary amino acids, and the hormonal control of intestinal function. Our current experimental system provides a unique opportunity for such studies. The set-up consists of controlled micro-tube feeding of the larvae in combination with metabolic tracer studies enabling us to quantify the intestinal proteolytic capacity, transfer kinetics of nutrients from gut to body and the metabolic fate of essential and non-essential amino acids. Data show that dietary free amino acids (FAA) are absorbed faster (about 3.5 times in Senegal sole and 10 times in Atlantic halibut) from the gut into the larval body tissues compared with the protein. The FAA was also assimilated with higher efficiency than the protein (>80% vs >60%). Our recent data indicate that a key intestinal regulatory peptide (cholecystokinin, CCK) is not present until two weeks after first feeding in Atlantic halibut. This raises the question of how digestion is regulated during this vital developmental window. In larval herring we have found a correlation between CCK and trypsin activity in larvae upon tube feeding dietary protein. The response was much lower in larvae fed FAA. We have recently demonstrated a marked, relatively rapid retrograde peristaltic activity in the pyloric region of larval Atlantic halibut, Hippoglossus hippoglossus L. in vitro and in vivo. This could provide a mechanism by which the fish can fill the pyloric caeca and seems also to be involved in mixing the chyme with digestive secretions in the region of the pyloric caeca. These findings will be discussed in relation to formulation of starter diets for marine fish.

(Department of Zoology, University of Bergen, Allégt 41, N5007 Bergen, Norway)


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